Purpose: To determine the maximum tolerated dose (MTD), toxicity spectrum, clinical activity, and biological effects…
There are no effective treatments for diffuse intrinsic pontine gliomas (DIPGs); these tumors cannot be…
The following represents disclosure information provided by authors of this manuscript. All relationships are considered…
DNX-2401 has won a $2 million grant from the Food and Drug Administration to support…
A common cold virus engineered to attack the most common and deadly of brain tumors…
Treatment with the investigational agent DNX-2401 resulted in 20% of a cohort of patients with…
Re-engineering a common cold virus to attack the deadliest kind of brain tumor extended the…
Findings from an early phase clinical trial that used a so-called “smart bomb” virus —…
Zika, polio and adenovirus are hardly the first trio that comes to mind when considering…
