Purpose: To determine the maximum tolerated dose (MTD), toxicity spectrum, clinical activity, and biological effects…
There are no effective treatments for diffuse intrinsic pontine gliomas (DIPGs); these tumors cannot be…
The following represents disclosure information provided by authors of this manuscript. All relationships are considered…
DNX-2401 (Delta-24-RGD; tasadenoturev) is a tumor-selective, replication-competent oncolytic adenovirus. Preclinical studies demonstrated antiglioma efficacy, but…
How oncolytic viruses are coming of age in cancer immunotherapy combinations After over two decades…
DNX-2401 has won a $2 million grant from the Food and Drug Administration to support…
Research on the potential of oncolytic viruses to treat various cancer types has waxed and…
A genetically engineered cold virus that attacks tumor cells and triggers an immune response significantly…
A common cold virus engineered to attack the most common and deadly of brain tumors…
